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  ADME Tox (ADME Toxicity Assays)

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ADME/Tox (ADME Toxicology) profiles define how a compound interacts with the rest of the body to cause activity and toxicity. To identify the ADME/Toxicology profile of a candidate drug, Beckman Coulter offers solutions that support a number of in vitro, in vivo, and Cytochrome P450 (CYP Inhibition Assay) techniques.

Beckman Coulter offers solutions supporting the following assay and analysis techniques:

  • In Vitro Permeability Analysis automating the PAMPA (Parallel Artificial Membrane Permeability Analysis) Method
  • Caco-2 Cell Differentiation
  • Cytochrome P450 Analysis (CYP Inhibition Assay)

 
Products Description Related Product Applications Complete Application Detail

Biomek® ADMETox Workstation

ADMETox Workstation. ADME toxicity assays for in vitro permeability measurements, automating the PAMPA method and Caco-2 assays. Laboratory Automation

Biomek® FXP Laboratory Automation Workstation

A fluorometric, LC-MS/MS based high throughput screening (HTS) method for Cytochrome P450 Inhibition Assay in a 384-well Plate Format. Laboratory Automation

DTX Series Multimode Detectors

With a variety of detection modes and plate formats from which to choose, the DTX series provides a nearly limitless number of Systems Biology application solutions. The DTX Series provides applications solutions for ADME Tox Assay, CACO-2 Assays, and Cytochrome P450 assays. Laboratory Automation

SAGIAN™ Core Systems

This automated solution has been allowed an increase in capacity, throughput and reliability for ADME Tox assays. Laboratory Automation
 


 

 
 
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